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Research Opportunities

Lab identifier: Health Services Research in Pediatric Surgery (Dept. of General Surgery, Boston Children’s Hospital)
Name: Shawn J Rangel, MD, MSCE
Contact Information: shawn.rangel@childrens.harvard.edu

Summary of research investigation & fellowship experience: We offer a three-year Fellowship in Clinical Effectiveness & Health Services Research, now accepting applications for the July, 2023-June, 2026 position. The three-year fellowship is designed for surgery residents who wish to pursue a career in pediatric surgery with a focus in health services and comparative effectiveness research. Ongoing research efforts include development of novel quality metrics and prioritization strategies for hospital-level comparative analysis, characterization of causes and financial implications of practice variation for resource-intensive surgical conditions, and development of best practices surrounding SSI prevention, antimicrobial stewardship, & management of pediatric appendicitis, among others. As an integral part of the fellowship, the Department of Surgery will sponsor the fellow to obtain a Master’s in Public Health with a focus in Clinical Effectiveness Research from the Harvard School of Public Health.

3-4 representative publications:

Hills-Dunlap JL, Melvin P, Graham DA, Kashtan MA, Anandalwar SP, Rangel SJ. Association of sociodemographic factors with adherence to age-specific guidelines for asymptomatic umbilical hernia repair in children. JAMA Pediatr. 2019 Jul 1;173(7):640-647.

Kashtan MA, Graham DA, Melvin P, Cameron DB, Anandalwar SP, Hills-Dunlap JL, Rangel SJ. Ceftriaxone with Metronidazole is superior to Cefoxitin in the treatment of uncomplicated appendicitis in children. Ann Surg. 2020 Mar 5. doi: 10.1097.

Cameron DB, Serres SK, Glass CC, Milliren CE, Graham DA, Anandalwar SP, Thangarajah H, Rangel SJ. Leveraging the incidence, burden, and fiscal implications of unplanned hospital revisits for the prioritization of prevention efforts in pediatric surgery. Ann Surg. 2020 Jan;271(1):191-199.

Cameron DB, Anandalwar SP, Graham DA, Melvin P, Serres SK, Dunlap JL, Kashtan K, Hall M, Saito JM, Barnhart DC, Kenney BD, Rangel SJ. Development and implications of an evidence-based and public health-relevant definition of complicated appendicitis in children. Ann Surg. 2020 May;271(5):962-968.

Posted on: 04/13/2021

Bariatric and Metabolic Surgery Research Lab
Lahey Hospital and Medical Center, Burlington MA

Division of General Surgery Dmitry Nepomnayshy MD MSc, Bariatric Surgeon
Email: dmitry.nepomnayshy@lahey.org

This 1 year research opportunity involves working closely with our clinical bariatric and metabolic surgery team as well as our basic science translational laboratory to develop research on how to improve the care of the morbidly obese patient. The scope of the research will be determined by the interests and abilities of the applicant.

We are a busy bariatric surgery service who work closely with a medical obesity treatment center. Together, we see thousands of patients per year, and we perform hundreds of primary and revisional bariatric surgery operations per year.

Representative Research:

Doyon, Christ, Sherman, Sullivan, Brams, Schnelldorfer, Nepomnayshy "Pre Operative Serum Micro RNA Profiles Associated With Weight Loss Following Bariatric Surgery" 2020 SOARD, 16:1802-1807

Wilson, Powell, Kim, Nepomnayshy "Obesity" FP Essent. 2020;492:1-48

Abdulhai, Sedeeq, Nepomnayshy "Does Obstructive Sleep Apnea Affect Perioperative Complications? A Retrospective Study Using a Modified NSQIP Database" 2020 World Journal of Surgery, 44:2609-2613

Posted on: 04/07/2021

Funded and accredited American College of Surgeons 1 year Simulation and Education Fellowship Lahey Hospital and Medical Center, Burlington MA

Division of Simulation and Professional Development, Dmitry Nepomnayshy MD MSc – Director.
Email: dmitry.nepomnayshy@lahey.org


The goal of this fellowship is to create leaders in medical education who are particularly interested in the use of simulation training to maximize student learning and help achieve institutional educational, patient safety and quality goals. Graduates of the Fellowship Program will obtain the skills necessary to lead graduate and postgraduate medical education programs as well as conduct research to advance the field of medical education through simulation.

This fellowship is intended for surgical or anesthesia residents to spend one year working and learning in the Lahey Simulation Center under the supervision of experienced faculty in order to develop their expertise in the field of simulation-based health professions education and achieve academic productivity to help advance their academic career. Educational content is supplemented through Lahey’s affiliations with professional development courses at Tufts University School of Medicine and Center for Medical Simulation (CMS), a Harvard-affiliated training center.

The fellow will participate in and lead research projects with mentorship from faculty and staff at the medical center. They will present and disseminate their research through participation at regional and national meetings and manuscript submissions. They will receive assistance in manuscript preparation and travel to present their work.

Representative papers:

Gabrysz-Forget, Nepomnayshy, Nguyen "Surgical Errors happen, but are Learners trained to Recover from them? A Survey of North American Surgical Residents and Fellows" 2020 J Surg Ed 77:1552-1561

Gabrysz-Forget, Rubin, Nepomnayshy, Dolan, Yarlagada “Development and Validation of a Novel Simulator for Parotidectomy and Facial Nerve Dissection” Otolargyngology Head and Neck Surgery (2020) On Line https://doi.org/10.1177/0194599820913587

Gabrysz-Forget, Alseidi, Ghaderi, Nepomnayshy "Practicing on the Advanced Training in Laparoscopic Suturing Curriculum (ATLAS): Is Mastery Learning In Residency Feasible to Achieve Expert Level Performance in Laparoscopic Suturing?" 2020 J Surg Ed 77:1138-1145

Posted on: 04/07/2021

Lab Identifier: Lahey Hospital & Medical Center, Department of Colon and Rectal Surgery
Name: Peter Marcello MD; Lisa Breen MD; Angela Kuhnen MD; David Kleiman MD MSc; Julia Saraidaridis MD MMSc; Jonathan Abelson MD MS
Contact Information: 781-883-4141; Email; Website

A summary of key projects: The Department of Colon and Rectal Surgery at Lahey Hospital and Medical Center continuously contributes to innovative research projects as part of an ongoing effort to enhance patient care and improve quality of life. Our group is routinely a study site for national trials to better understand the role of surgery in various colorectal conditions. Current research and clinical trials employ a prospectively maintained institutional database to identify predictors of improved patient outcomes. Specific clinical research projects include long-term follow-up of ileal anal pouch function, the use of stem cells to treat complex perianal fistulas, use of an endoscopic step-up approach to advanced neoplastic colorectal polyps, and the impact of patient-reported outcome surveys to determine optimal surgical management. Our group is also interested in enhancing the diversity and effectiveness of the surgical workforce through several collaborative mixed-methods research studies.

  • Cohan JN, Donahue C, Pantel HJ, Ricciardi R, Kleiman DA, Read TE, Marcello PW. Endoscopic Step Up: A Colon-Sparing Alternative to Colectomy to Improve Outcomes and Reduce Costs for Patients With Advanced Neoplastic Polyps. Dis Colon Rectum. 2020 Jun;63(6):842-849.

  • Pantel HJ, Jasak LJ, Ricciardi R, Marcello PW, Roberts PL, Schoetz DJ Jr, Read TE. Should They Stay or Should They Go? The Utility of C-Reactive Protein in Predicting Readmission and Anastomotic Leak After Colorectal Resection. Dis Colon Rectum. 2019 Feb;62(2):241-247.

  • Fleshman J, Branda ME, Sargent DJ, Boller AM, George VV, Abbas MA, Peters WR Jr, Maun DC, Chang GJ, Herline A, Fichera A, Mutch MG, Wexner SD, Whiteford MH, Marks J, Birnbaum E, Margolin DA, Larson DW, Marcello PW, Posner MC, Read TE, Monson JRT, Wren SM, Pisters PWT, Nelson H. Disease-free Survival and Local Recurrence for Laparoscopic Resection Compared With Open Resection of Stage II to III Rectal Cancer: Follow-up Results of the ACOSOG Z6051 Randomized Controlled Trial. Ann Surg. 2019 Apr;269(4):589-595.

  • Hall JF, Roberts PL, Ricciardi R, Read T, Scheirey C, Wald C, Marcello PW, Schoetz DJ. Long-term follow-up after an initial episode of diverticulitis: what are the predictors of recurrence? Dis Colon Rectum. 2011 Mar;54(3):283-8.

Posted on: 03/25/2021

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